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pre transformed human brain cdna library in pact2  (TaKaRa)


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    Structured Review

    TaKaRa pre transformed human brain cdna library in pact2
    Pre Transformed Human Brain Cdna Library In Pact2, supplied by TaKaRa, used in various techniques. Bioz Stars score: 93/100, based on 157 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pre+transformed+human+brain+cdna+library+in+pact2/Human+Kidney+Matchmaker+cDNA+Library+pACT2/pm36594364-472-11-21
    Average 93 stars, based on 157 article reviews
    pre transformed human brain cdna library in pact2 - by Bioz Stars, 2026-10
    93/100 stars

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    Related Articles

    other:

    Article Title: Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease.
    Article Snippet: Synaptic dysfunction caused by soluble b-amyloid peptide (Ab) is a hallmark of early-stage Alzheimer’s disease (AD), and is tightly linked to cognitive decline.. By yet unknown mechanisms, Ab suppresses the transcriptional activity of cAMP-responsive elementbinding protein (CREB), a master regulator of cell survival and plasticity-related gene expression.. Here, we report that Ab elicits nucleocytoplasmic trafficking of Jacob, a protein that connects a NMDA-receptor-derived signalosome to CREB, in AD patient brains and mouse hippocampal neurons.

    cDNA Library Assay:

    Article Title: Jacob‐induced transcriptional inactivation of CREB promotes Aβ‐induced synapse loss in Alzheimer's disease
    Article Snippet: .. The YTH screening for Jacob interaction partners was performed using a pre‐transformed human brain cDNA Library in pACT2 (Matchmaker‐GAL4 Two‐Hybrid II; Clontech) as described previously (Helmuth et al , ; Dieterich et al , ). .. The yeast strains AH109 and Y187 as a partner (both from Clontech) were used.



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